Mechanical + Fluidic Assessment of Syringe Driver Designs

Project Objectives: – Analysis will seek to understand elements of two (2) syringe driver designs which impact final product robustness, manufacturability, and overall accuracy. – Where appropriate, physics models will be created using Excel, Matlab, or similar tools. – The main purpose of this analysis is to understand potential failure modes and product risks and then to propose methods of mitigating and testing the device for said issues. – Consultant to provide recommendations as to the fitness of the syringe driver design for manufacturing scale-up. – Where appropriate, physics models will be created using Excel, Matlab, or similar tools. -- Encoders on the syringe driver lead screws are used to measure dosing and flowrates. -- The syringe drivers are driven by a lead screw which is actuated via stepper motor. Project Scope: Phase 1: Knowledge Transfer Phase 2: Perform comprehensive state-transition analysis (anchored by visual mind map) – Identify and map standard states – Brainstorm non-intended/alternative states and then map them in the transition analysis Phase 3: Theoretical assessment of critical states and interfaces – Quasi-static analysis baseline (pressures, forces, deformations of parts) – Where needed, employ dynamic analysis (impacts, fluid flows etc.) – Strengths of materials (FEM, fundamental hand calculations) where appropriate – Tolerance analysis and impact of limit conditions on overall accuracy – Design for manufacturability assessment Phase 4: Create preliminary DFMEA to itemize and rank potential failure modes Phase 5: Summary Report – Describe analysis methodology and important assumptions – Highlight potential failure modes – Identify risk areas in the design – Recommend mitigations to observed issues Deliverables: Documentation: – State-transition mind maps – Free body diagrams, as applicable – Appraisal documents, files (Excel, Matlab, or similar) – High-level preliminary DFMEA document – Final recommendation – Summary Report Additional Requirements: 1. All work related to this project is to be owned by us. A signed agreement and a NDA is required. 2. Please PM if you have any specific questions.