Visuals that explain how a eukaryotic microbe enters the body and destroys tumors. 5-7 slides

  • Status: Closed
  • Prize: $260
  • Entries Received: 46
  • Winner: hassanahmad93

Contest Brief

Hello, IN 3-5 DAYS, I wish to create visuals that illustrate how a novel cancer therapy works . I know it's very little time but I am interested in "quick and dirty" not "3D glamorous". Here is what I would like for each slide:
1. Anterior whole body view showing tumor sites highlighted (eg. thymus, lung, ovary, skin, omentum and lymph nodes). A syringe injects "therapeutic microbes" into the thigh intramuscularly OR directly into a tumor. The microbes (nucleated cells) find their way and concentrate in the tumors but leave normal tissue alone.
2. Tumor mass view. A generic view of a tumor (a cluster of cancer cells enclosed in a protective Tumor Microenvironment) with the cellular microbes transiting easily this barrier that keeps out the body's normal immune system. As the microbes penetrate the Microenvironment, it weakens its protective shielding from the immune system.
3. Cancer cell view. close up showing membrane and nucleus at least. Endocytosis lapse illustratrion. The cancer cell endocytoses a microbe that has a "master key" to the cell membrane, invaginating it and then by pinocytosis, create a vacuole within the cytoplasm. In those vacuoles, the microbe replicates until it breaks out, fragmenting the cancer cell releasing daughter microbes and also cancer antigens and fragments that are processed by the immune system.
4. Tumor view. a) The microbial lysis is reinforced by T-cells activated by prior release of cancer fragments until the tumor Microenvironment is destroyed, leaving the microbes exposed to the body's immune system. b) Immune cells (T-cells and others) can now move into the tumor that had been weakened by the microbes and "eat" the cancer cells.
5. The immune system then eliminates the free roaming microbes that emerge from the tumor, in a matter of days.

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For inspiration, here is a link to a very glossy 3D animation of an oncolytic virus therapy. https://www.transgene.fr/en/technology/ There won't be enough time for that level of graphics so if only 2D is possible, that's fine.

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Please use royalty-free images if possible such as at Servier Medical Art or Wikicommons. However, if there are images at Dreamstime.com that would be very useful, I could set up an account there.

Thanks

Thanks

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Employer Feedback

“He knew the subject matter, carefully read and addressed the project requirements and delivered on time. While others may have proposed graphics more colorful or 3D images, they did not fully grasp my requirements and some graphics overshadowed the message. Hassan provided something in very short time that conveys what I wanted.”

Profile image scottliht, United States.

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Public Clarification Board

  • Farrukh Saeed
    Farrukh Saeed
    • 4 years ago

    #27

    • 4 years ago
  • rabbiinni
    rabbiinni
    • 4 years ago

    Hi Scott, Hope you're doing great today. Please do review my entry #26 . Many thanks. Best, Mariya.

    • 4 years ago
  • iambisw
    iambisw
    • 4 years ago

    check entry #49 , this is what , you need in your presentation

    • 4 years ago
  • hr260755
    hr260755
    • 4 years ago

    sir can you please tell me more about it??

    • 4 years ago
  • iambisw
    iambisw
    • 4 years ago

    So you need 5 animations in total, i will try to submit them with in the time limit.

    • 4 years ago
    View 1 more message Processing...
    1. iambisw
      iambisw
      • 4 years ago

      doing them

      • 4 years ago
    2. iambisw
      iambisw
      • 4 years ago

      i have completed 60 % , just wait 2 hours, i will submit them

      • 4 years ago
  • CorneliaTeo
    CorneliaTeo
    • 4 years ago

    please check #29

    • 4 years ago
  • salihobouriche
    salihobouriche
    • 4 years ago

    Please check video #4 https://youtu.be/w1CJAugOpwI

    • 4 years ago
  • Farrukh Saeed
    Farrukh Saeed
    • 4 years ago

    in powerpoint

    • 4 years ago
  • shaba5566
    shaba5566
    • 4 years ago

    4 slide done

    • 4 years ago
  • salihobouriche
    salihobouriche
    • 4 years ago

    Working on it , i'll submit before time limit

    • 4 years ago
  • FinoDesignINK
    FinoDesignINK
    • 4 years ago

    HOLA:)

    • 4 years ago
    1. scottliht
      Contest Holder
      • 4 years ago

      Que tal?

      • 4 years ago
  • yunitasarike1
    yunitasarike1
    • 4 years ago

    WORKING

    • 4 years ago

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